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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Gradual Reduction with The Sinclair Method: Why It Works

Gradual Reduction with The Sinclair Method: Why It Works

Gradual Reduction with The Sinclair Method: Why It WorksBruce Rose
Published on: 11/09/2025

That’s where The Sinclair Method (TSM) shines. This innovative approach offers an alternative: gradual reduction, using the medication naltrexone to change your brain’s response to alcohol, one drink at a time.

The Sinclair Method (TSM)
Rethink Drink – Leading Providers of the Sinclair Method in the UK

Rethink Drink – Leading Providers of the Sinclair Method in the UK

Rethink Drink – Leading Providers of the Sinclair Method in the UKBruce Rose
Published on: 08/09/2025

At Rethink Drink, we're proud to be leading the charge in reshaping how the UK approaches alcohol recovery. For too long, individuals seeking change have faced limited choices: abstinence-only programmes, rigid systems, and shame-based narratives. We exist to offer a smarter, science-backed alternative — The Sinclair Method (TSM).

The Sinclair Method (TSM)
Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method

Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method

Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair MethodBruce Rose
Published on: 05/09/2025

Over the past few months, major UK tabloids like The Sun have published several high-profile stories on naltrexone — a £3 tablet nicknamed the "Ozempic for drinkers". It’s been hailed by some as a revolutionary option for those wanting to cut back or quit alcohol.

The Sinclair Method (TSM)
Does The Sinclair Method Work? Exploring Its Success and Science

Does The Sinclair Method Work? Exploring Its Success and Science

Does The Sinclair Method Work? Exploring Its Success and ScienceBruce Rose
Published on: 04/09/2025

The Sinclair Method (TSM) is a medication-based treatment for Alcohol Use Disorder (AUD) that allows individuals to continue drinking while retraining their brain’s response to alcohol. The cornerstone of this method is naltrexone, an opioid blocker that dulls the endorphin rush typically triggered by alcohol.

The Sinclair Method (TSM)
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